The World Health Organization in collaboration with the Papua New Guinea National Department of Health (NDoH), hosted the Stage 2 Consultation Workshop on the National Health Research Agenda (NHRA) 2025–2030, which started today and will end on Wednesday May 14th, 2025. This event, held at the Airways Hotel in Port Moresby, brought together key stakeholders from across the country’s health sector, including representatives from provincial health authorities, research institutions, government agencies, development partners, and academia. After the successful Stage 1 Consultation in November 2024, which identified over 60 research questions, this second stage aims to refine and prioritize those topics while establishing a foundation for implementing the agenda. Over two days, participants will take part in collaborative sessions to finalize the research priorities, discuss implementation strategies, and provide feedback on the draft NHRA document. The consultation also highlights the significance of sustainable domestic funding and cross-sector partnerships to transform the Agenda into a dynamic strategy that fosters genuine improvements in health outcomes. The NHRA serves as a key initiative within the National Health Plan 2021–2030, designed to ensure that health research in the country is locally driven, evidence-based, and addresses the most urgent health challenges. The NDoH expresses heartfelt gratitude to all participants for their dedication and input, as well as to WHO for its ongoing assistance. Together, they are developing a research agenda aimed at enhancing PNG’s healthcare system and bettering the lives of all citizens of Papua New Guinea.